# OnCo record lag3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/lag3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "lag3" ;
  schema:name "LAG-3"@en ;
  schema:description "LAG-3 is the third immune brake to reach approval, combined with PD-1 blockade in melanoma."@en ;
  schema:url <https://onco.cc/targets/lag3/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/LAG3>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6476>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000089692>, <https://www.uniprot.org/uniprotkb/P18627/entry>, <https://www.ncbi.nlm.nih.gov/gene/3902> ;
  schema:citation <https://en.wikipedia.org/wiki/LAG3> ;
  onco:tag "checkpoint" ;
  schema:alternateName "LAG3" ;
  onco:targetClass "checkpoint" ;
  onco:firstDescribed "1990"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/hlx26/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/>, <https://onco.cc/pathways/t-cell-exhaustion/> .