# OnCo record lats2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/lats2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "lats2" ;
  schema:name "LATS2"@en ;
  schema:alternateName "large tumor suppressor kinase 2"@en, "Serine/threonine-protein kinase LATS2"@en, "LATS2" ;
  schema:description "LATS2 (Serine/threonine-protein kinase LATS2) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as an oncogene driver and a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Mesothelioma, Skin cancer, Colorectal cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/lats2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6515>, <https://www.uniprot.org/uniprotkb/Q9NRM7/entry>, <https://www.ncbi.nlm.nih.gov/gene/26524>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000150457> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6515>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000150457>, <https://www.uniprot.org/uniprotkb/Q9NRM7/entry>, <https://www.ncbi.nlm.nih.gov/gene/26524> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/mesothelioma/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/pleural-mesothelioma/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/paediatric-low-grade-glioma/>, <https://onco.cc/cancers/melanoma/> .