# OnCo record leucovorin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/leucovorin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "leucovorin" ;
  schema:name "Leucovorin (folinic acid)"@en ;
  schema:alternateName "Leucovorin Calcium"@en, "Folinic acid"@en, "Calcium folinate"@en, "Levoleucovorin (Fusilev, Khapzory)"@en, "Wellcovorin / generic" ;
  schema:description "Leucovorin is not a cancer drug in itself: it rescues normal tissue after high-dose methotrexate and, given with fluorouracil, makes that chemotherapy work better, which is why it appears in FOLFOX, FOLFIRI and FOLFIRINOX."@en ;
  schema:url <https://onco.cc/drugs/leucovorin/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Folinic_acid> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=leucovorin%20calcium> ;
  onco:status "established" ;
  onco:tag "gap-fill", "generic" ;
  onco:modality "Reduced folate (rescue agent and chemotherapy modulator)" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/dhfr/>, <https://onco.cc/targets/tyms/> ;
  onco:drugs <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/fluorouracil/> ;
  onco:trials <https://onco.cc/trials/int-0116/>, <https://onco.cc/trials/nct07775287/>, <https://onco.cc/trials/nct07412613/>, <https://onco.cc/trials/nct07621718/>, <https://onco.cc/trials/nct06107413/>, <https://onco.cc/trials/nct05846867/>, <https://onco.cc/trials/nct04421820/>, <https://onco.cc/trials/nct06493760/>, <https://onco.cc/trials/nct06901531/>, <https://onco.cc/trials/nct07056777/>, <https://onco.cc/trials/nct06662786/>, <https://onco.cc/trials/nct03505320/>, <https://onco.cc/trials/nct06750094/>, <https://onco.cc/trials/nct07238283/>, <https://onco.cc/trials/nct06703177/>, <https://onco.cc/trials/nct05859750/>, <https://onco.cc/trials/nct04919226/> .