# OnCo record lgr5-gene (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/lgr5-gene/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "lgr5-gene" ;
  schema:name "LGR5"@en ;
  schema:alternateName "leucine rich repeat containing G protein-coupled receptor 5"@en, "Leucine-rich repeat-containing G protein-coupled receptor 5"@en, "HG38"@en, "GPR67"@en, "GPR49"@en, "LGR5" ;
  schema:description "LGR5 (Leucine-rich repeat-containing G protein-coupled receptor 5) is a protein on the cell surface. The public catalogues list it as a drug target, a biomarker and an antigen, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer and Sarcomas."@en ;
  schema:url <https://onco.cc/targets/lgr5-gene/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4504>, <https://www.uniprot.org/uniprotkb/O75473/entry>, <https://www.ncbi.nlm.nih.gov/gene/8549>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000139292> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "surface-antigen" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4504>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000139292>, <https://www.uniprot.org/uniprotkb/O75473/entry>, <https://www.ncbi.nlm.nih.gov/gene/8549> ;
  onco:related <https://onco.cc/collections/civic/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/sarcoma/> ;
  onco:drugs <https://onco.cc/drugs/petosemtamab/> ;
  onco:pathways <https://onco.cc/pathways/wnt/> ;
  onco:trials <https://onco.cc/trials/nct05759728/> .