# OnCo record lilrb1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/lilrb1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "lilrb1" ;
  schema:name "LILRB1 (ILT2)"@en ;
  schema:alternateName "ILT2"@en, "LIR-1"@en, "CD85j"@en, "leukocyte immunoglobulin like receptor B1"@en, "LILRB1" ;
  schema:description "LILRB1 is a brake on macrophages, dendritic cells and some NK and T cells that reads ordinary HLA class I, so any cell showing HLA is protected. Antibodies that block it, with or without LILRB2, are in early trials."@en ;
  schema:url <https://onco.cc/targets/lilrb1/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6605>, <https://www.uniprot.org/uniprotkb/Q8NHL6/entry>, <https://www.ncbi.nlm.nih.gov/gene/10859>, <https://clinicaltrials.gov/study/NCT04913337> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "checkpoint" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6605>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104972>, <https://www.uniprot.org/uniprotkb/Q8NHL6/entry>, <https://www.ncbi.nlm.nih.gov/gene/10859> ;
  onco:related <https://onco.cc/targets/lilrb2/>, <https://onco.cc/targets/hla-a/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/> .