# OnCo record liposarcoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/liposarcoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "liposarcoma" ;
  schema:name "Liposarcoma"@en ;
  schema:alternateName "Well-differentiated liposarcoma (atypical lipomatous tumour)"@en, "Dedifferentiated liposarcoma"@en, "Myxoid liposarcoma"@en, "Pleomorphic liposarcoma"@en ;
  schema:description "Liposarcoma is a cancer of fat cells that comes in four different forms: two driven by extra copies of the MDM2 gene, one by a fusion gene that makes it unusually sensitive to radiotherapy and trabectedin, and one that behaves like other aggressive sarcomas. Surgery is the mainstay and MDM2 inhibitors are the most promising drugs in trials."@en ;
  schema:url <https://onco.cc/cancers/liposarcoma/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Liposarcoma> ;
  schema:citation <https://en.wikipedia.org/wiki/Liposarcoma> ;
  onco:tag "subtype-page" ;
  onco:related <https://onco.cc/cancers/leiomyosarcoma/>, <https://onco.cc/cancers/retroperitoneal-sarcoma/>, <https://onco.cc/cancers/undifferentiated-pleomorphic-sarcoma/>, <https://onco.cc/cancers/myxofibrosarcoma/>, <https://onco.cc/cancers/extremity-soft-tissue-sarcoma/>, <https://onco.cc/cancers/synovial-sarcoma/> ;
  onco:drugs <https://onco.cc/drugs/brigimadlin/> ;
  onco:trials <https://onco.cc/trials/sarc028/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-esmo-sts-guideline-gronchi-ann-oncol-2021/>, <https://onco.cc/key-papers/paper-strass-lancet-oncol-2020/>, <https://onco.cc/key-papers/paper-eribulin-liposarcoma-schoffski-lancet-2016/>, <https://onco.cc/key-papers/paper-trabectedin-vs-dacarbazine-demetri-jco-2016/> ;
  onco:pipeline <https://onco.cc/technologies/mdm2-inhibitors/>, <https://onco.cc/drugs/eribulin/> ;
  onco:standardOfCare <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/drugs/trabectedin/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/eribulin/>, <https://onco.cc/drugs/trabectedin/>, <https://onco.cc/targets/mdm2/> .