# OnCo record lomustine (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/lomustine/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "lomustine" ;
  schema:name "Lomustine (CCNU)"@en ;
  schema:description "An old chemotherapy pill used when glioblastoma comes back, and the control arm most new glioblastoma drugs must beat."@en ;
  schema:url <https://onco.cc/drugs/lomustine/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Lomustine> ;
  owl:sameAs <http://www.wikidata.org/entity/Q415378> ;
  schema:citation <https://en.wikipedia.org/wiki/Lomustine> ;
  onco:status "standard-of-care" ;
  onco:modality "Oral nitrosourea chemotherapy" ;
  schema:alternateName "Gleostine" ;
  onco:approval "US 1976: Brain tumours after surgery/radiation; Hodgkin lymphoma" ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/idh-mutant-astrocytoma/>, <https://onco.cc/cancers/oligodendroglioma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/nextsource-biotechnology/> ;
  onco:terms <https://onco.cc/terms/blood-brain-barrier/> ;
  onco:trials <https://onco.cc/trials/rtog-9402/>, <https://onco.cc/trials/eortc-26951/>, <https://onco.cc/trials/actuate-1801/>, <https://onco.cc/trials/nct04762069/> .