# OnCo record lsd1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/lsd1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "lsd1" ;
  schema:name "LSD1 (KDM1A)"@en ;
  schema:alternateName "LSD1"@en, "lysine-specific demethylase 1"@en, "lysine demethylase 1A"@en, "AOF2"@en, "KDM1A" ;
  schema:description "LSD1 is an enzyme that removes small chemical tags from the proteins DNA is wound around, switching genes off or on. Many cancers carry a lot of it and it helps keep leukaemia cells immature; several LSD1 inhibitors have been tested in blood cancers and solid tumours."@en ;
  schema:url <https://onco.cc/targets/lsd1/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29079>, <https://www.uniprot.org/uniprotkb/O60341/entry>, <https://www.ncbi.nlm.nih.gov/gene/23028>, <https://doi.org/10.3389/fphar.2023.1120911> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29079>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000004487>, <https://www.uniprot.org/uniprotkb/O60341/entry>, <https://www.ncbi.nlm.nih.gov/gene/23028> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/sclc/> ;
  onco:technologies <https://onco.cc/technologies/lsd1-inhibitors/> ;
  onco:drugs <https://onco.cc/drugs/rec-4539/> .