# OnCo record lyma (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/lyma/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "lyma", "NCT00921414" ;
  schema:name "LyMa"@en ;
  schema:alternateName "Rituximab maintenance after autologous transplantation in mantle cell lymphoma"@en, "LyMa trial"@en ;
  schema:description "Three years of an antibody every two months after a stem cell transplant kept younger people with mantle cell lymphoma in remission longer and helped them live longer."@en ;
  schema:url <https://onco.cc/trials/lyma/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00921414>, <https://doi.org/10.1056/NEJMoa1701769> ;
  onco:status "positive" ;
  onco:tag "lymphoma-evidence" ;
  onco:phase "3" ;
  schema:startDate "2008-09" ;
  onco:cancers <https://onco.cc/cancers/mantle-cell-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/>, <https://onco.cc/fronts/cell-therapy/> ;
  onco:technologies <https://onco.cc/technologies/monoclonal-antibody/> ;
  onco:targets <https://onco.cc/targets/cd20/>, <https://onco.cc/targets/ccnd1/> ;
  onco:drugs <https://onco.cc/drugs/rituximab/>, <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/cytarabine/>, <https://onco.cc/drugs/cisplatin/> ;
  onco:terms <https://onco.cc/terms/maintenance-therapy/>, <https://onco.cc/terms/autologous-transplant/>, <https://onco.cc/terms/lymphoma-tx-maintenance/>, <https://onco.cc/terms/lymphoma-tx-transplant-role/> ;
  onco:trials <https://onco.cc/trials/triangle/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-lyma-rituximab-maintenance-after-transplant-mantle-cell-nejm-2017/> .