# OnCo record lymphoma-bio-lymphgen (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/lymphoma-bio-lymphgen/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "lymphoma-bio-lymphgen" ;
  schema:name "LymphGen and the genetic clusters of large B-cell lymphoma"@en ;
  schema:alternateName "LymphGen"@en, "MCD subtype"@en, "BN2 subtype"@en, "EZB subtype"@en, "N1 subtype"@en, "DLBCL genetic subtypes"@en, "Chapuy clusters"@en ;
  schema:description "Sequencing shows that large B-cell lymphoma is at least seven diseases, each defined by which faults occur together. The classification explains a great deal about how the disease behaves and currently changes almost nothing about how it is treated."@en ;
  schema:url <https://onco.cc/terms/lymphoma-bio-lymphgen/> ;
  schema:dateModified "2026-09-30"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa1801445>, <https://doi.org/10.1038/s41591-018-0016-8>, <https://doi.org/10.1016/j.ccell.2020.03.015> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/primary-cns-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/cgp/>, <https://onco.cc/technologies/wes-wgs/> ;
  onco:targets <https://onco.cc/targets/myd88/>, <https://onco.cc/targets/cd79b/>, <https://onco.cc/targets/bcl6/>, <https://onco.cc/targets/notch1/>, <https://onco.cc/targets/notch2/>, <https://onco.cc/targets/ezh2/>, <https://onco.cc/targets/bcl2/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/cdkn2a/> ;
  onco:pathways <https://onco.cc/pathways/bcr-signalling/>, <https://onco.cc/pathways/inflammation-nfkb/>, <https://onco.cc/pathways/germinal-centre-reaction/> ;
  onco:terms <https://onco.cc/terms/cell-of-origin/>, <https://onco.cc/terms/lymphoma-bio-cell-of-origin-in-practice/>, <https://onco.cc/terms/ngs/> .