# OnCo record lymphoma-decision-transplant-or-car-t (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/lymphoma-decision-transplant-or-car-t/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "lymphoma-decision-transplant-or-car-t" ;
  schema:name "Transplant or CAR-T at second line in diffuse large B-cell lymphoma"@en ;
  schema:alternateName "Second-line DLBCL decision"@en, "Autologous transplant or CAR-T"@en, "ZUMA-7 decision"@en, "Early relapse large B-cell lymphoma"@en ;
  schema:description "If a large B-cell lymphoma comes back within a year of first treatment, two trials found that engineered T cells worked better than salvage chemotherapy followed by a transplant of the person's own stem cells, and a third trial of a different T-cell product found no difference. If it comes back later, the transplant route is still standard."@en ;
  schema:url <https://onco.cc/terms/lymphoma-decision-transplant-or-car-t/> ;
  schema:dateModified "2026-10-01"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa2116133>, <https://doi.org/10.1056/NEJMoa2301665>, <https://doi.org/10.1056/NEJMoa2116596>, <https://lymphoma-action.org.uk/information-and-support/lymphoma-treatment/car-t-cell-therapy>, <https://lymphoma-action.org.uk/information-and-support/lymphoma-treatment/stem-cell-transplants/self-autologous-stem-cell>, <https://lymphoma-action.org.uk/information-and-support/types-lymphoma/non-hodgkin-lymphoma/diffuse-large-b-cell-lymphoma>, <https://lymphoma-action.org.uk/information-and-support/living-and-beyond-lymphoma/lymphoma-comes-back-relapses-or-doesnt-respond> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/primary-mediastinal-b-cell-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/autologous-stem-cell-transplant/>, <https://onco.cc/technologies/car-t/> ;
  onco:terms <https://onco.cc/terms/lymphoma-tx-transplant-role/>, <https://onco.cc/terms/lymphoma-tx-car-t-pathway/>, <https://onco.cc/terms/autologous-transplant/>, <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/>, <https://onco.cc/terms/lymphoma-living-infection-years-after/>, <https://onco.cc/terms/lymphoma-decision-local-or-car-t-centre/> ;
  onco:trials <https://onco.cc/trials/zuma-7/>, <https://onco.cc/trials/transform/>, <https://onco.cc/trials/belinda/> .
