# OnCo record lymphoma-transformation (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/lymphoma-transformation/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "lymphoma-transformation" ;
  schema:name "Transformation of an indolent lymphoma"@en ;
  schema:alternateName "histological transformation"@en, "transformed lymphoma"@en, "Richter transformation"@en, "high-grade transformation"@en ;
  schema:description "A slow-growing lymphoma can change into a fast-growing one. It usually announces itself as one node growing much faster than the others, a sudden rise in lactate dehydrogenase, or new fevers and weight loss in somebody who has been stable for years. It is treated as the aggressive lymphoma it has become, not as the one it came from."@en ;
  schema:url <https://onco.cc/terms/lymphoma-transformation/> ;
  schema:dateModified "2026-09-29"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41375-022-01620-2>, <https://www.cancer.gov/types/lymphoma/hp/adult-nhl-treatment-pdq> ;
  onco:tag "heme", "lymphoma" ;
  onco:related <https://onco.cc/terms/lymphoma-indolent-versus-aggressive/>, <https://onco.cc/terms/lymphoma-tx-watch-and-wait/>, <https://onco.cc/cancers/richter-transformation-cll/> ;
  onco:cancers <https://onco.cc/cancers/follicular-lymphoma/>, <https://onco.cc/cancers/marginal-zone-lymphoma/>, <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> .