# OnCo record lymphoma-tx-bispecific-step-up (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/lymphoma-tx-bispecific-step-up/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "lymphoma-tx-bispecific-step-up" ;
  schema:name "CD20 bispecific antibodies: step-up dosing, fixed duration and what it is like to take one"@en ;
  schema:alternateName "Step-up dosing"@en, "T-cell engager lymphoma"@en, "Glofitamab schedule"@en, "Epcoritamab schedule"@en, "Mosunetuzumab schedule"@en ;
  schema:description "Bispecific antibodies grab a lymphoma cell with one arm and a T cell with the other. The first doses are deliberately tiny because the first full dose is what causes fever and low blood pressure; after that most people take them as an outpatient."@en ;
  schema:url <https://onco.cc/terms/lymphoma-tx-bispecific-step-up/> ;
  schema:dateModified "2026-09-29"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.22.01725>, <https://doi.org/10.1016/S1470-2045(22)00335-7>, <https://doi.org/10.1016/j.annonc.2024.08.2239> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/follicular-lymphoma/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/marginal-zone-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/bispecific-antibody/> ;
  onco:drugs <https://onco.cc/drugs/glofitamab/>, <https://onco.cc/drugs/epcoritamab/>, <https://onco.cc/drugs/mosunetuzumab/>, <https://onco.cc/drugs/odronextamab/>, <https://onco.cc/drugs/obinutuzumab/>, <https://onco.cc/drugs/tocilizumab/> ;
  onco:terms <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/>, <https://onco.cc/terms/lymphoma-tx-crs-icans/>, <https://onco.cc/terms/lymphoma-tx-immunoglobulin-replacement/> ;
  onco:trials <https://onco.cc/trials/epcore-nhl-1/>, <https://onco.cc/trials/epcore-dlbcl-1/>, <https://onco.cc/trials/starglo/>, <https://onco.cc/trials/sunmo/> .