# OnCo record lynch-associated-colorectal-cancer (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/lynch-associated-colorectal-cancer/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "lynch-associated-colorectal-cancer" ;
  schema:name "Lynch syndrome-associated colorectal cancer"@en ;
  schema:alternateName "Lynch syndrome-associated colorectal cancer (inherited mismatch repair variant; about 1 to 4 percent of colon cancers)"@en, "Lynch syndrome (hereditary dMMR, ~3%)"@en, "Hereditary non-polyposis colorectal cancer"@en, "HNPCC"@en, "Lynch syndrome bowel cancer"@en, "Mismatch repair germline colorectal cancer"@en ;
  schema:description "Lynch syndrome-associated bowel cancer is bowel cancer in someone born with a fault in one of the genes that proofread DNA copying errors. The tumours tend to arise younger and on the right side, they carry the mismatch repair defect that makes immunotherapy work, and the diagnosis changes the care of the whole family as well as the care of the patient."@en ;
  schema:url <https://onco.cc/cancers/lynch-associated-colorectal-cancer/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Lynch_syndrome> ;
  schema:citation <https://doi.org/10.1158/1055-9965.epi-16-0693>, <https://doi.org/10.1136/gutjnl-2015-309675>, <https://doi.org/10.1016/s0140-6736(20)30366-4>, <https://doi.org/10.1136/gutjnl-2019-319915>, <https://www.nice.org.uk/guidance/ng151/chapter/Recommendations>, <https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bowel-cancer/risk-factors>, <https://doi.org/10.1111/his.13975> ;
  onco:tag "gi", "colorectal", "subtype-page" ;
  onco:related <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/msi-high-colorectal/>, <https://onco.cc/cancers/fap-associated-colorectal-cancer/>, <https://onco.cc/cancers/early-onset-colorectal/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/colon-cancer/>, <https://onco.cc/cancers/rectal-cancer/> ;
  onco:technologies <https://onco.cc/technologies/msi-mmr-testing/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/aspirin-cancer-prevention/>, <https://onco.cc/technologies/chemoprevention/> ;
  onco:terms <https://onco.cc/terms/lynch-syndrome/>, <https://onco.cc/terms/msi/>, <https://onco.cc/terms/mlh1-promoter-methylation/>, <https://onco.cc/terms/germline-vs-somatic/>, <https://onco.cc/terms/colonoscopy-surveillance-intervals/>, <https://onco.cc/terms/serrated-pathway/> ;
  onco:standardOfCare <https://onco.cc/technologies/msi-mmr-testing/>, <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/terms/lynch-syndrome/>, <https://onco.cc/terms/mlh1-promoter-methylation/>, <https://onco.cc/technologies/aspirin-cancer-prevention/>, <https://onco.cc/terms/colonoscopy/>, <https://onco.cc/terms/colonoscopy-surveillance-intervals/>, <https://onco.cc/terms/colectomy/>, <https://onco.cc/technologies/chemoprevention/> .