# OnCo record lynch-syndrome (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/lynch-syndrome/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "lynch-syndrome" ;
  schema:name "Lynch syndrome"@en ;
  schema:description "Lynch syndrome is the most common inherited cancer syndrome: a faulty mismatch-repair gene raises lifetime bowel cancer risk to 40-80% and also endometrial and other cancers."@en ;
  schema:url <https://onco.cc/terms/lynch-syndrome/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Lynch_syndrome> ;
  schema:citation <https://en.wikipedia.org/wiki/Lynch_syndrome>, <https://doi.org/10.1158/1055-9965.epi-16-0693>, <https://doi.org/10.1136/gutjnl-2015-309675>, <https://doi.org/10.1136/gutjnl-2019-319915> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/msi-high-pdac/>, <https://onco.cc/cancers/lynch-associated-colorectal-cancer/>, <https://onco.cc/cancers/prostate/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/technologies/chemoprevention/>, <https://onco.cc/technologies/colorectal-screening/> ;
  onco:terms <https://onco.cc/terms/msi/>, <https://onco.cc/terms/germline-vs-somatic/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-moreira-lynch-syndrome-identification-jama-2012/>, <https://onco.cc/key-papers/paper-ligtenberg-epcam-deletion-msh2-silencing-nat-genet-2009/>, <https://onco.cc/key-papers/paper-weisenberger-cimp-braf-mlh1-colorectal-nat-genet-2006/>, <https://onco.cc/key-papers/paper-abida-msi-prostate-checkpoint-blockade-jama-oncol-2019/>, <https://onco.cc/key-papers/paper-guedes-msh2-loss-primary-prostate-ccr-2017/> .