# OnCo record malignant-peripheral-nerve-sheath-tumour (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/malignant-peripheral-nerve-sheath-tumour/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "malignant-peripheral-nerve-sheath-tumour" ;
  schema:name "Malignant peripheral nerve sheath tumour (MPNST)"@en ;
  schema:alternateName "MPNST"@en, "Neurofibrosarcoma (historic)"@en, "Malignant schwannoma (historic)"@en ;
  schema:description "Malignant peripheral nerve sheath tumour is a sarcoma that grows from the covering of a nerve, most often in people with neurofibromatosis type 1 when a benign plexiform neurofibroma turns malignant. Surgery with radiotherapy is the only cure; chemotherapy with doxorubicin and ifosfamide shrinks some tumours, and drugs targeting the tumour's lost NF1 and PRC2 brakes are in trials."@en ;
  schema:url <https://onco.cc/cancers/malignant-peripheral-nerve-sheath-tumour/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Malignant_peripheral_nerve_sheath_tumor> ;
  schema:citation <https://en.wikipedia.org/wiki/Malignant_peripheral_nerve_sheath_tumor> ;
  onco:tag "subtype-page" ;
  onco:related <https://onco.cc/cancers/extremity-soft-tissue-sarcoma/>, <https://onco.cc/cancers/desmoid-tumour/> ;
  onco:pipeline <https://onco.cc/drugs/selumetinib/>, <https://onco.cc/drugs/mirdametinib/>, <https://onco.cc/targets/mek/>, <https://onco.cc/pathways/ras-mapk/> ;
  onco:standardOfCare <https://onco.cc/technologies/limb-salvage-surgery/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/trials/eortc-62012/>, <https://onco.cc/drugs/etoposide/>, <https://onco.cc/technologies/mri/>, <https://onco.cc/technologies/pet-ct/>, <https://onco.cc/drugs/selumetinib/>, <https://onco.cc/drugs/mirdametinib/> .