# OnCo record maoa (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/maoa/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "maoa" ;
  schema:name "MAO-A (MAOA)"@en ;
  schema:alternateName "MAO-A"@en, "monoamine oxidase A"@en, "MAOA" ;
  schema:description "MAO-A is an enzyme best known for breaking down serotonin and other signalling chemicals in the brain; medicines called MAO inhibitors, used for some neurological disorders, block it. Aggressive prostate cancers carry more of it, and a MAO-A inhibitor designed to stay out of the brain is in an early prostate cancer trial."@en ;
  schema:url <https://onco.cc/targets/maoa/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6833>, <https://www.uniprot.org/uniprotkb/P21397/entry>, <https://www.ncbi.nlm.nih.gov/gene/4128>, <https://doi.org/10.1172/JCI70982> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6833>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000189221>, <https://www.uniprot.org/uniprotkb/P21397/entry>, <https://www.ncbi.nlm.nih.gov/gene/4128> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:drugs <https://onco.cc/drugs/itr-251/> .
