# OnCo record map2k4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/map2k4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "map2k4" ;
  schema:name "MAP2K4"@en ;
  schema:alternateName "mitogen-activated protein kinase kinase 4"@en, "Dual specificity mitogen-activated protein kinase kinase 4"@en, "MEK4"@en, "JNKK1"@en, "PRKMK4"@en, "MKK4"@en, "MAPKK4"@en, "SAPKK1"@en, "SKK1"@en, "SEK1"@en, "SERK1"@en, "MAP2K4" ;
  schema:description "MAP2K4 is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response."@en ;
  schema:url <https://onco.cc/targets/map2k4/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6844>, <https://www.uniprot.org/uniprotkb/P45985/entry>, <https://www.ncbi.nlm.nih.gov/gene/6416>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000065559> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6844>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000065559>, <https://www.uniprot.org/uniprotkb/P45985/entry>, <https://www.ncbi.nlm.nih.gov/gene/6416> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/biliary-tract-cancer/> .