# OnCo record master-protocol (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/master-protocol/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "master-protocol" ;
  schema:name "Master protocol (platform, basket and umbrella trials)"@en ;
  schema:alternateName "platform trial"@en, "basket trial"@en, "umbrella trial"@en, "master protocol"@en, "master protocols"@en, "platform trials"@en, "basket trials"@en, "umbrella trials"@en, "multi-arm multi-stage"@en, "MAMS"@en, "adaptive platform trial"@en ;
  schema:description "A master protocol is one trial framework that tests several treatments, several cancers or both under a single set of rules, so new drugs can join and leave without a new trial being built each time. Platform trials add and drop arms over the years, basket trials test one drug across cancers that share a mutation, and umbrella trials test several drugs matched to biomarkers within one cancer."@en ;
  schema:url <https://onco.cc/terms/master-protocol/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Basket_trial> ;
  schema:citation <https://en.wikipedia.org/wiki/Basket_trial>, <https://www.fda.gov/media/120721/download> ;
  onco:related <https://onco.cc/trials/i-spy-1/>, <https://onco.cc/trials/i-spy-2/>, <https://onco.cc/trials/i-spy-2-2/>, <https://onco.cc/trials/stampede/>, <https://onco.cc/trials/myelomatch/>, <https://onco.cc/trials/pediatric-match/>, <https://onco.cc/trials/lung-map/>, <https://onco.cc/trials/lung-map-s1400i/>, <https://onco.cc/trials/lung-map-s1800a/>, <https://onco.cc/trials/nci-match/>, <https://onco.cc/trials/combomatch/>, <https://onco.cc/trials/tapur/>, <https://onco.cc/trials/dart-s1609/>, <https://onco.cc/trials/plasmamatch/>, <https://onco.cc/trials/gbm-agile/>, <https://onco.cc/trials/precision-promise/>, <https://onco.cc/trials/beat-aml-master-trial/>, <https://onco.cc/trials/determine-trial/>, <https://onco.cc/trials/national-lung-matrix-trial/>, <https://onco.cc/trials/focus4/>, <https://onco.cc/trials/alchemist/>, <https://onco.cc/trials/mypathway/>, <https://onco.cc/trials/i-predict/>, <https://onco.cc/trials/winther/>, <https://onco.cc/trials/cupisco/>, <https://onco.cc/trials/target-national/>, <https://onco.cc/terms/basket-umbrella-platform/>, <https://onco.cc/terms/seamless-adaptive/>, <https://onco.cc/terms/interim-analysis/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/digital-twins-trials/>, <https://onco.cc/technologies/n-of-1-platforms/>, <https://onco.cc/technologies/cgp/>, <https://onco.cc/technologies/ai-trial-matching/> ;
  onco:trials <https://onco.cc/trials/i-spy-1/>, <https://onco.cc/trials/i-spy-2/>, <https://onco.cc/trials/i-spy-2-2/>, <https://onco.cc/trials/stampede/>, <https://onco.cc/trials/myelomatch/>, <https://onco.cc/trials/pediatric-match/>, <https://onco.cc/trials/lung-map/>, <https://onco.cc/trials/lung-map-s1400i/>, <https://onco.cc/trials/lung-map-s1800a/>, <https://onco.cc/trials/nci-match/>, <https://onco.cc/trials/combomatch/>, <https://onco.cc/trials/tapur/>, <https://onco.cc/trials/dart-s1609/>, <https://onco.cc/trials/plasmamatch/>, <https://onco.cc/trials/gbm-agile/>, <https://onco.cc/trials/precision-promise/>, <https://onco.cc/trials/beat-aml-master-trial/>, <https://onco.cc/trials/determine-trial/>, <https://onco.cc/trials/national-lung-matrix-trial/>, <https://onco.cc/trials/focus4/>, <https://onco.cc/trials/alchemist/>, <https://onco.cc/trials/mypathway/>, <https://onco.cc/trials/i-predict/>, <https://onco.cc/trials/winther/>, <https://onco.cc/trials/cupisco/>, <https://onco.cc/trials/target-national/> ;
  onco:people <https://onco.cc/people/laura-esserman/>, <https://onco.cc/people/nicholas-james/>, <https://onco.cc/people/mahesh-parmar/>, <https://onco.cc/people/roy-herbst/>, <https://onco.cc/people/keith-flaherty/>, <https://onco.cc/people/razelle-kurzrock/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-trial-enrolment/>, <https://onco.cc/bottlenecks/b-rare-cancers/> .