# OnCo record mc-vc-pabc (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/mc-vc-pabc/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "mc-vc-pabc" ;
  schema:name "mc-Val-Cit-PABC"@en ;
  schema:alternateName "valine-citrulline linker"@en, "vc-MMAE"@en, "mc-VC-PABC"@en ;
  schema:description "The mc-Val-Cit-PABC linker is the workhorse of the vedotin ADCs: a valine-citrulline dipeptide cut by cathepsin B, releasing MMAE with a bystander effect."@en ;
  schema:url <https://onco.cc/terms/mc-vc-pabc/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Brentuximab_vedotin> ;
  schema:citation <https://doi.org/10.1038/nbt832> ;
  onco:related <https://onco.cc/terms/mmae/>, <https://onco.cc/terms/bystander-effect/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:drugs <https://onco.cc/drugs/enfortumab-vedotin/>, <https://onco.cc/drugs/brentuximab-vedotin/>, <https://onco.cc/drugs/tisotumab-vedotin/>, <https://onco.cc/drugs/telisotuzumab-vedotin/>, <https://onco.cc/drugs/disitamab-vedotin/> ;
  onco:terms <https://onco.cc/terms/linker/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-doronina-nat-biotechnol/> .