# OnCo record mecom (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/mecom/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "mecom" ;
  schema:name "MECOM"@en ;
  schema:alternateName "MDS1 and EVI1 complex locus"@en, "Histone-lysine N-methyltransferase MECOM"@en, "MDS1-EVI1"@en, "PRDM3"@en, "KMT8E"@en, "MDS1"@en, "EVI1"@en, "MECOM" ;
  schema:description "MECOM (Histone-lysine N-methyltransferase MECOM) is a protein that switches other genes on and off. The public catalogues list it as an oncogene driver, a tumour suppressor, a biomarker and a fusion partner, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Breast cancer, Prostate cancer, Endometrial cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/mecom/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3498>, <https://www.uniprot.org/uniprotkb/Q03112/entry>, <https://www.ncbi.nlm.nih.gov/gene/2122>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000085276> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3498>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000085276>, <https://www.uniprot.org/uniprotkb/Q03112/entry>, <https://www.ncbi.nlm.nih.gov/gene/2122> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/aml/> .