# OnCo record med12 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/med12/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "med12" ;
  schema:name "MED12"@en ;
  schema:alternateName "mediator complex subunit 12"@en, "Mediator of RNA polymerase II transcription subunit 12"@en, "CAGH45"@en, "OPA1"@en, "TRAP230"@en, "KIAA0192"@en, "ARC240"@en, "Kto"@en, "TNRC11"@en, "FGS1"@en, "MED12" ;
  schema:description "MED12 (Mediator of RNA polymerase II transcription subunit 12) is a protein that switches other genes on and off. The public catalogues list it as an oncogene driver and a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Prostate cancer, Cervical cancer, Endometrial cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/med12/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11957>, <https://www.uniprot.org/uniprotkb/Q93074/entry>, <https://www.ncbi.nlm.nih.gov/gene/9968>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000184634> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11957>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000184634>, <https://www.uniprot.org/uniprotkb/Q93074/entry>, <https://www.ncbi.nlm.nih.gov/gene/9968> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/cll/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/glioblastoma/> .