# OnCo record megestrol-progestins (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/megestrol-progestins/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "megestrol-progestins" ;
  schema:name "Progestins (megestrol acetate, medroxyprogesterone, levonorgestrel IUD)"@en ;
  schema:alternateName "Levonorgestrel"@en, "Levonorgestrel intrauterine device"@en, "Megestrol acetate"@en, "Medroxyprogesterone"@en, "Oral progestins"@en, "Megace; Mirena (IUD)" ;
  schema:description "Progesterone-like hormones that can reverse early endometrial cancer in women who want to keep their uterus, and control advanced hormone-sensitive disease."@en ;
  schema:url <https://onco.cc/drugs/megestrol-progestins/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Megestrol_acetate> ;
  owl:sameAs <http://www.wikidata.org/entity/Q6808975> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Progestins> ;
  onco:status "approved" ;
  onco:modality "Hormonal therapy (progestin)" ;
  onco:approval "US 1971: Palliative treatment of advanced endometrial and breast cancer (megestrol)" ;
  onco:cancers <https://onco.cc/cancers/endometrial/> ;
  onco:technologies <https://onco.cc/technologies/endocrine-therapy/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/> ;
  onco:pathways <https://onco.cc/pathways/er-signaling/> ;
  onco:trials <https://onco.cc/trials/nct03463252/>, <https://onco.cc/trials/nct02990728/>, <https://onco.cc/trials/nct01594879/> .