# OnCo record meis1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/meis1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "meis1" ;
  schema:name "MEIS1"@en ;
  schema:alternateName "Meis homeobox 1"@en, "MEIS1" ;
  schema:description "MEIS1 is HOXA9's partner in keeping leukaemia cells immature. The two are switched on together in KMT2A-rearranged and NPM1-mutant leukaemia, and switched off together when a menin inhibitor works."@en ;
  schema:url <https://onco.cc/targets/meis1/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7000>, <https://www.uniprot.org/uniprotkb/O00470/entry>, <https://www.ncbi.nlm.nih.gov/gene/4211> ;
  onco:tag "wave5-target" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7000>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143995>, <https://www.uniprot.org/uniprotkb/O00470/entry>, <https://www.ncbi.nlm.nih.gov/gene/4211> ;
  onco:related <https://onco.cc/drugs/revumenib/>, <https://onco.cc/drugs/ziftomenib/>, <https://onco.cc/targets/menin/>, <https://onco.cc/targets/hoxa9/>, <https://onco.cc/targets/kmt2a/>, <https://onco.cc/targets/npm1/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/aml-npm1-kmt2a/> ;
  onco:technologies <https://onco.cc/technologies/menin-inhibitors/> ;
  onco:pathways <https://onco.cc/pathways/menin-kmt2a/>, <https://onco.cc/pathways/aml-signalling/> .