# OnCo record met-amplification (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/met-amplification/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "met-amplification" ;
  schema:name "MET amplification (bypass resistance)"@en ;
  schema:description "When lung cancer switches on the MET receptor to bypass a blocked EGFR pill."@en ;
  schema:url <https://onco.cc/terms/met-amplification/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/C-Met> ;
  schema:citation <https://doi.org/10.1126/scitranslmed.3002003> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:targets <https://onco.cc/targets/met/>, <https://onco.cc/targets/egfr/> ;
  onco:drugs <https://onco.cc/drugs/amivantamab/>, <https://onco.cc/drugs/telisotuzumab-vedotin/> ;
  onco:terms <https://onco.cc/terms/resistance/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-engelman-met-amplification-gefitinib-resistance-science-2007/>, <https://onco.cc/key-papers/paper-yu-acquired-resistance-rebiopsy-egfr-ccr-2013/>, <https://onco.cc/key-papers/paper-awad-met-exon-14-mutations-lung-jco-2016/>, <https://onco.cc/key-papers/paper-sequist-genotypic-histological-evolution-egfr-resistance-sci-transl-med-2011/> .