# OnCo record metastatic-cascade (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/metastatic-cascade/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "metastatic-cascade" ;
  schema:name "The metastatic cascade"@en ;
  schema:description "How cancer spreads: cells leave the tumour, squeeze into blood or lymph vessels, survive the journey, exit into a new organ, often sleep there for years, and finally grow. Metastasis causes about 90% of cancer deaths."@en ;
  schema:url <https://onco.cc/pathways/metastatic-cascade/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Metastasis> ;
  owl:sameAs <http://www.wikidata.org/entity/Q181876> ;
  schema:citation <https://doi.org/10.1038/nature17038>, <https://doi.org/10.1016/j.cell.2023.03.003> ;
  onco:tag "mechanism" ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/liquid-biopsy/>, <https://onco.cc/technologies/sbrt/>, <https://onco.cc/technologies/single-cell-spatial/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/francis-crick/>, <https://onco.cc/institutions/cold-spring-harbor/>, <https://onco.cc/institutions/dkfz/> ;
  onco:pathways <https://onco.cc/pathways/emt/>, <https://onco.cc/pathways/tumor-dormancy/>, <https://onco.cc/pathways/tumor-microenvironment/>, <https://onco.cc/pathways/clonal-evolution/> ;
  onco:terms <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/oligometastatic/>, <https://onco.cc/terms/disseminated-tumor-cells/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-massague-nature/>, <https://onco.cc/key-papers/paper-gerstberger-cell/> .