# OnCo record michel-sadelain (person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/people/michel-sadelain/>
  a schema:Person ;
  onco:kind "person" ;
  schema:identifier "michel-sadelain" ;
  schema:name "Michel Sadelain"@en ;
  schema:description "Designed the second-generation CAR with a CD28 costimulatory domain that made CAR-T therapy work."@en ;
  schema:url <https://onco.cc/people/michel-sadelain/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/?term=Sadelain%20M%5BAuthor%5D%20chimeric%20antigen%20receptor> ;
  onco:tag "cell-therapy", "car-t", "engineering" ;
  schema:jobTitle "Director, Columbia Initiative in Cell Engineering and Therapy, Columbia University Irving Medical Center" ;
  schema:sameAs <https://orcid.org/0000-0002-9031-8025> ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/in-vivo-car-t/> ;
  onco:targets <https://onco.cc/targets/cd19/> ;
  onco:institutions <https://onco.cc/institutions/columbia-hicc/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-zuma-1-axi-cel-nejm-2017/> ;
  onco:journals <https://onco.cc/journals/science-translational-medicine/> ;
  schema:affiliation <https://onco.cc/institutions/columbia-hicc/> .