# OnCo record micrornas-in-cancer (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/micrornas-in-cancer/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "micrornas-in-cancer" ;
  schema:name "MicroRNAs in cancer"@en ;
  schema:alternateName "KEGG hsa05206"@en, "MicroRNAs in cancer"@en ;
  schema:description "This KEGG map collects the small RNA molecules (microRNAs) that are switched up or down in nine common cancers and shows which oncogenes and tumour suppressors they silence. It matters because a single microRNA can dial down dozens of genes at once, so losing or gaining one reshapes whole signalling routes."@en ;
  schema:url <https://onco.cc/pathways/micrornas-in-cancer/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://www.kegg.jp/pathway/hsa05206>, <https://doi.org/10.1038/nrc1997> ;
  onco:related <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/p53-cell-cycle/>, <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:targets <https://onco.cc/targets/ezh2/>, <https://onco.cc/targets/tp53/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/bcl2/> ;
  onco:drugs <https://onco.cc/drugs/decitabine/>, <https://onco.cc/drugs/azacitidine/>, <https://onco.cc/drugs/tazemetostat/>, <https://onco.cc/drugs/sotorasib/>, <https://onco.cc/drugs/adagrasib/>, <https://onco.cc/drugs/alpelisib/>, <https://onco.cc/drugs/capivasertib/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/p53-cell-cycle/>, <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-calin-nat-rev-cancer/> .