# OnCo record mindact (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/mindact/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "mindact", "NCT00433589" ;
  schema:name "MINDACT"@en ;
  schema:description "MINDACT showed that women whose early breast cancer looked high-risk to doctors but low-risk on the 70-gene MammaPrint test could skip chemotherapy: those who did met the trial's prespecified safety threshold, and about 46% of clinically high-risk women could avoid chemotherapy. Women aged 50 or under may still gain from it."@en ;
  schema:url <https://onco.cc/trials/mindact/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00433589>, <https://doi.org/10.1056/NEJMoa1602253>, <https://doi.org/10.1016/S1470-2045(21)00007-3> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2007-02" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/hr-positive-early-high-risk/> ;
  onco:technologies <https://onco.cc/technologies/rna-seq/> ;
  onco:drugs <https://onco.cc/drugs/mammaprint/> ;
  onco:companies <https://onco.cc/companies/curie-nki-eortc/>, <https://onco.cc/companies/big/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-piccart-lancet-oncol/>, <https://onco.cc/key-papers/paper-cardoso-n-engl-j-med/>, <https://onco.cc/key-papers/paper-mindact-ann-oncol-2014/> .