# OnCo record mitf (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/mitf/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "mitf" ;
  schema:name "MITF"@en ;
  schema:alternateName "melanocyte inducing transcription factor"@en, "Microphthalmia-associated transcription factor"@en, "bHLHe32"@en, "WS2A"@en, "WS2"@en, "MITF" ;
  schema:description "MITF (Microphthalmia-associated transcription factor) is a protein that switches other genes on and off. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Skin cancer, Breast cancer, Ovarian cancer and 2 more."@en ;
  schema:url <https://onco.cc/targets/mitf/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7105>, <https://www.uniprot.org/uniprotkb/O75030/entry>, <https://www.ncbi.nlm.nih.gov/gene/4286>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000187098> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7105>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000187098>, <https://www.uniprot.org/uniprotkb/O75030/entry>, <https://www.ncbi.nlm.nih.gov/gene/4286> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/melanoma/> ;
  onco:pathways <https://onco.cc/pathways/melanoma-signalling/> .
