# OnCo record mitomycin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/mitomycin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "mitomycin" ;
  schema:name "Mitomycin C"@en ;
  schema:description "The chemotherapy given with radiation to cure anal cancer without surgery, used as a bladder instillation after tumour resection, and since 2020-25 in gel form for upper-tract and recurrent bladder cancers."@en ;
  schema:url <https://onco.cc/drugs/mitomycin/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Mitomycin_C> ;
  owl:sameAs <http://www.wikidata.org/entity/Q19856779> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Jelmyto>, <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=mitomycin> ;
  onco:status "approved" ;
  onco:tag "gap-fill", "generic" ;
  onco:modality "Alkylating antibiotic (bioreductive)" ;
  schema:alternateName "Mutamycin / Jelmyto / Zusduri" ;
  onco:approval "US 1974: Disseminated gastric or pancreatic adenocarcinoma (with other agents)", "US 2020: Low-grade upper tract urothelial carcinoma (mitomycin pyelocalyceal gel)", "US 2025: Recurrent low-grade intermediate-risk NMIBC (intravesical gel)" ;
  onco:cancers <https://onco.cc/cancers/anal/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/appendiceal/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/localised-anal-cancer/>, <https://onco.cc/cancers/low-grade-appendiceal-mucinous-neoplasm/>, <https://onco.cc/cancers/appendiceal-adenocarcinoma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/bcg-and-intravesical-therapy/>, <https://onco.cc/technologies/hipec/>, <https://onco.cc/technologies/imrt-igrt/> ;
  onco:trials <https://onco.cc/trials/nct06211764/>, <https://onco.cc/trials/nct07566156/>, <https://onco.cc/trials/nct04241185/> .