# OnCo record mixed-phenotype-acute-leukaemia (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/mixed-phenotype-acute-leukaemia/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "mixed-phenotype-acute-leukaemia" ;
  schema:name "Mixed-phenotype acute leukaemia"@en ;
  schema:alternateName "MPAL"@en, "Mixed phenotype acute leukemia"@en, "Acute biphenotypic leukaemia"@en, "Acute biphenotypic leukemia"@en, "Bilineal acute leukaemia"@en, "Acute leukaemia of ambiguous lineage"@en, "Mixed-phenotype acute leukaemia"@en ;
  schema:description "Mixed-phenotype acute leukaemia is a rare acute leukaemia whose cells carry markers of both lymphoid and myeloid lines, so it fits neither acute lymphoblastic nor acute myeloid leukaemia. Pooled evidence favours starting with the drugs used for acute lymphoblastic leukaemia, adding a targeted drug when the Philadelphia chromosome is present, and a stem cell transplant in first remission."@en ;
  schema:url <https://onco.cc/cancers/mixed-phenotype-acute-leukaemia/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Mixed-phenotype_acute_leukemia> ;
  schema:citation <https://www.cancer.gov/types/leukemia/patient/adult-all-treatment-pdq>, <https://doi.org/10.1038/s41375-022-01613-1>, <https://doi.org/10.1038/s41375-018-0058-4>, <https://doi.org/10.1002/cncr.32552> ;
  onco:tag "subtype-page", "wave4", "haematologic", "rare" ;
  onco:related <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-npm1-kmt2a/>, <https://onco.cc/cancers/burkitt-leukaemia/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/> ;
  onco:drugs <https://onco.cc/drugs/imatinib/>, <https://onco.cc/drugs/dasatinib/>, <https://onco.cc/drugs/cytarabine/>, <https://onco.cc/drugs/blinatumomab/> ;
  onco:terms <https://onco.cc/terms/allogeneic-transplant/> ;
  onco:trials <https://onco.cc/trials/nct05433532/> ;
  onco:standardOfCare <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/aml/>, <https://onco.cc/drugs/imatinib/>, <https://onco.cc/drugs/dasatinib/>, <https://onco.cc/terms/allogeneic-transplant/>, <https://onco.cc/technologies/mrd-testing/> .