# OnCo record mlh1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/mlh1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "mlh1" ;
  schema:name "MLH1"@en ;
  schema:alternateName "mutL homolog 1"@en, "DNA mismatch repair protein Mlh1"@en, "HNPCC"@en, "FCC2"@en, "HNPCC2"@en, "MLH-1"@en, "COCA2"@en, "MLH1" ;
  schema:description "MLH1 (DNA mismatch repair protein Mlh1) is a gene. The public catalogues list it as a drug target, a biomarker and a DNA repair gene, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer, Ovarian cancer, Endometrial cancer and 4 more."@en ;
  schema:url <https://onco.cc/targets/mlh1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7127>, <https://www.uniprot.org/uniprotkb/P40692/entry>, <https://www.ncbi.nlm.nih.gov/gene/4292>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000076242> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7127>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000076242>, <https://www.uniprot.org/uniprotkb/P40692/entry>, <https://www.ncbi.nlm.nih.gov/gene/4292> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/lung-cancer/> ;
  onco:drugs <https://onco.cc/drugs/ventana-mmr-rxdx/> ;
  onco:pathways <https://onco.cc/pathways/colorectal-cancer-signalling/>, <https://onco.cc/pathways/endometrial-cancer-signalling/>, <https://onco.cc/pathways/mismatch-repair-msi/> .