# OnCo record molecular-response (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/molecular-response/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "molecular-response" ;
  schema:name "Molecular response (MMR, MR4, treatment-free remission)"@en ;
  schema:alternateName "major molecular response"@en, "MR4"@en, "MR4.5"@en, "deep molecular response"@en, "complete molecular response"@en, "BCR-ABL1 transcript"@en, "BCR::ABL1 IS"@en, "International Scale"@en, "treatment-free remission"@en, "TFR"@en, "molecular relapse"@en, "cytogenetic response"@en, "complete cytogenetic response"@en, "early molecular response"@en, "cytogenetic responses"@en, "molecular responses"@en ;
  schema:description "In chronic myeloid leukaemia, how far the leukaemia gene signal in the blood has fallen, measured in logs: a 1,000-fold drop is a major molecular response, a 10,000-fold drop (MR4) is 'deep'. Deep responses held for two years let some patients stop their pills."@en ;
  schema:url <https://onco.cc/terms/molecular-response/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Chronic_myelogenous_leukemia> ;
  schema:citation <https://en.wikipedia.org/wiki/Chronic_myelogenous_leukemia> ;
  onco:related <https://onco.cc/terms/philadelphia-chromosome/>, <https://onco.cc/terms/umrd/>, <https://onco.cc/terms/tki-term/>, <https://onco.cc/terms/fixed-duration/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/>, <https://onco.cc/fronts/diagnostics/> ;
  onco:drugs <https://onco.cc/drugs/imatinib/>, <https://onco.cc/drugs/asciminib/>, <https://onco.cc/drugs/nilotinib/>, <https://onco.cc/drugs/dasatinib/> .