# OnCo record monaleesa-2 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/monaleesa-2/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "monaleesa-2", "NCT01958021" ;
  schema:name "MONALEESA-2"@en ;
  schema:description "The first CDK4/6 inhibitor trial to show that adding the pill to hormone therapy makes women live longer, by about a year."@en ;
  schema:url <https://onco.cc/trials/monaleesa-2/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01958021> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2013-12-17" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/cdk46-inhibitor/> ;
  onco:targets <https://onco.cc/targets/cdk4-6/>, <https://onco.cc/targets/estrogen-receptor/> ;
  onco:drugs <https://onco.cc/drugs/ribociclib/> ;
  onco:companies <https://onco.cc/companies/novartis/> ;
  onco:people <https://onco.cc/people/gabriel-hortobagyi/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-monaleesa-2-n-engl-j-med-2016/>, <https://onco.cc/key-papers/paper-monaleesa-2-n-engl-j-med-2022-update/> .