# OnCo record mrd-kinetics-models (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/mrd-kinetics-models/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "mrd-kinetics-models" ;
  schema:name "Residual disease kinetics (BCR-ABL halving and ctDNA slopes)"@en ;
  schema:description "The speed at which a molecular marker falls during treatment predicts outcome better than a single level: BCR-ABL halving time in chronic myeloid leukaemia and circulating tumour DNA slopes in solid tumours are now used to judge response within weeks."@en ;
  schema:url <https://onco.cc/technologies/mrd-kinetics-models/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/nature03669> ;
  onco:status "established" ;
  onco:tag "mathematical-model" ;
  onco:cancers <https://onco.cc/cancers/cml/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/colorectal/> ;
  onco:sections <https://onco.cc/fronts/ai-computation/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/ngs-mrd-clonoseq/>, <https://onco.cc/technologies/continuous-ctdna-monitoring/>, <https://onco.cc/technologies/flow-cytometry-mrd/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-michor-nature/> .