# OnCo record mrna-lnp-manufacturing (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/mrna-lnp-manufacturing/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "mrna-lnp-manufacturing" ;
  schema:name "mRNA and lipid nanoparticle manufacturing"@en ;
  schema:description "An mRNA cancer vaccine is made without cells: a DNA template is copied into RNA by an enzyme in a tank, cleaned up, and wrapped in tiny fat bubbles. For personalised vaccines the whole run is done once for each patient, against that patient's own tumour mutations, in a few weeks."@en ;
  schema:url <https://onco.cc/technologies/mrna-lnp-manufacturing/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.fda.gov/regulatory-information/search-fda-guidance-documents/chemistry-manufacturing-and-control-cmc-information-human-gene-therapy-investigational-new-drug>, <https://en.wikipedia.org/wiki/MRNA_vaccine> ;
  onco:status "phase-3" ;
  onco:tag "manufacturing-wave" ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/nsclc/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/plasmid-dna-manufacturing/>, <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/single-use-bioprocessing/>, <https://onco.cc/technologies/sterile-fill-finish/>, <https://onco.cc/technologies/cell-therapy-cold-chain/>, <https://onco.cc/technologies/shared-antigen-vaccine/> ;
  onco:drugs <https://onco.cc/drugs/intismeran-autogene/>, <https://onco.cc/drugs/autogene-cevumeran/> ;
  onco:companies <https://onco.cc/companies/moderna/>, <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/merck/>, <https://onco.cc/companies/aldevron/>, <https://onco.cc/companies/touchlight/>, <https://onco.cc/companies/thermo-fisher/>, <https://onco.cc/companies/lonza/> .