# OnCo record mss-pmmr (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/mss-pmmr/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "mss-pmmr" ;
  schema:name "Microsatellite-stable (MSS) / mismatch-repair proficient (pMMR)"@en ;
  schema:alternateName "MSS"@en, "pMMR"@en, "microsatellite-stable"@en, "microsatellite stable"@en, "mismatch repair proficient"@en, "mismatch-repair proficient"@en, "MMR-proficient"@en, "MMR proficient"@en, "MSI-low"@en, "MSS/pMMR"@en ;
  schema:description "The 'normal' result on the mismatch-repair test: the tumour has intact DNA spell-checking and few mutations. It describes about 95% of metastatic colorectal cancers and means checkpoint inhibitors alone are unlikely to work."@en ;
  schema:url <https://onco.cc/terms/mss-pmmr/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Microsatellite_instability> ;
  schema:citation <https://en.wikipedia.org/wiki/Microsatellite_instability> ;
  onco:related <https://onco.cc/terms/msi/>, <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/immuno-oncology/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/endometrial/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/>, <https://onco.cc/fronts/diagnostics/> ;
  onco:trials <https://onco.cc/trials/checkmate-8hw/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-eng-imblaze370-atezolizumab-cobimetinib-colorectal-lancet-oncol-2019/>, <https://onco.cc/key-papers/paper-tauriello-tgfbeta-immune-evasion-colorectal-nature-2018/>, <https://onco.cc/key-papers/paper-bullock-botensilimab-balstilimab-mss-colorectal-nat-med-2024/>, <https://onco.cc/key-papers/paper-calon-stromal-gene-expression-poor-prognosis-colorectal-nat-genet-2015/> .