# OnCo record myc-bcl2-double-expressor (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/myc-bcl2-double-expressor/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "myc-bcl2-double-expressor" ;
  schema:name "Double expressor: MYC and BCL2 protein together by immunohistochemistry"@en ;
  schema:alternateName "Double expressor lymphoma"@en, "DEL"@en, "MYC and BCL2 co-expression"@en, "MYC IHC"@en, "BCL2 IHC"@en ;
  schema:description "A stain showing that a lymphoma makes a lot of both the growth protein MYC and the survival protein BCL2, without the genes being rearranged. It predicts a worse course, but on its own it does not change the treatment."@en ;
  schema:url <https://onco.cc/biomarkers/myc-bcl2-double-expressor/> ;
  schema:dateModified "2026-09-30"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2011.41.0985>, <https://doi.org/10.1182/blood-2012-06-435842> ;
  onco:tag "biomarker", "lymphoma" ;
  onco:related <https://onco.cc/biomarkers/double-hit-rearrangement/>, <https://onco.cc/biomarkers/bcl2-rearrangement/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:technologies <https://onco.cc/technologies/histopathology-ihc/> ;
  onco:targets <https://onco.cc/targets/myc-gene/>, <https://onco.cc/targets/bcl2/> ;
  onco:pathways <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:terms <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/cell-of-origin/> .