# OnCo record mycn-amp (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/mycn-amp/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "mycn-amp" ;
  schema:name "MYCN amplification"@en ;
  schema:alternateName "MYCN amplification"@en, "MYCN-amplified"@en, "MYCN amp"@en, "N-myc amplification"@en, "MYCN-amplified neuroblastoma"@en, "MYCN FISH"@en ;
  schema:description "MYCN amplification, more than four times the normal copy number of the gene on FISH, marks the most aggressive fifth of neuroblastomas and puts a child in the high-risk group whatever their age or stage. No drug targets it; it decides how much treatment is given."@en ;
  schema:url <https://onco.cc/biomarkers/mycn-amp/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.2008.16.6785>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d66bdf0d-9d65-45de-ae5b-a58617c27492> ;
  onco:tag "biomarker", "paediatric", "no-approval" ;
  onco:related <https://onco.cc/biomarkers/tp53-del17p/> ;
  onco:cancers <https://onco.cc/cancers/neuroblastoma/>, <https://onco.cc/cancers/neuroblastoma-high-risk/>, <https://onco.cc/cancers/neuroblastoma-intermediate-risk/> ;
  onco:drugs <https://onco.cc/drugs/dinutuximab/> ;
  onco:terms <https://onco.cc/terms/mycn-amplification/>, <https://onco.cc/terms/gene-amplification/>, <https://onco.cc/terms/fish/>, <https://onco.cc/terms/segmental-chromosomal-aberrations/> .