# OnCo record mypathway (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/mypathway/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "mypathway", "NCT02091141" ;
  schema:name "MyPathway"@en ;
  schema:alternateName "My Pathway"@en, "MyPathway basket"@en ;
  schema:description "MyPathway was Roche's basket trial: six of its approved drugs given to people whose tumours carried the matching target but in a cancer the drug was never approved for. Its clearest win was trastuzumab plus pertuzumab in HER2-amplified bowel cancer, which became a guideline option."@en ;
  schema:url <https://onco.cc/trials/mypathway/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02091141>, <https://doi.org/10.1200/JCO.2017.75.3780>, <https://doi.org/10.1016/S1470-2045(18)30904-5>, <https://doi.org/10.1158/2159-8290.CD-21-0450> ;
  onco:status "completed" ;
  onco:phase "2" ;
  schema:startDate "2014-04-14" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/terms/rare-cancers/>, <https://onco.cc/cancers/gallbladder/>, <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/biliary-tract-cancer/> ;
  onco:technologies <https://onco.cc/technologies/cgp/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/monoclonal-antibody/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/pertuzumab/>, <https://onco.cc/drugs/erlotinib/>, <https://onco.cc/drugs/vemurafenib/>, <https://onco.cc/drugs/cobimetinib/>, <https://onco.cc/drugs/vismodegib/>, <https://onco.cc/drugs/alectinib/>, <https://onco.cc/drugs/atezolizumab/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/master-protocol/>, <https://onco.cc/terms/basket-umbrella-platform/>, <https://onco.cc/terms/tumour-agnostic/>, <https://onco.cc/terms/tmb/>, <https://onco.cc/terms/gallbladder-cancer-in-biliary-trials/> ;
  onco:trials <https://onco.cc/trials/nct04589845/> ;
  onco:people <https://onco.cc/people/funda-meric-bernstam/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-javle-mypathway-her2-biliary-lancet-oncol-2021/>, <https://onco.cc/key-papers/paper-friedman-cancer-discov/>, <https://onco.cc/key-papers/paper-hainsworth-j-clin-oncol/>, <https://onco.cc/key-papers/paper-mypathway-lancet-oncol-2019/> .