# OnCo record nadina (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/nadina/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "nadina", "NCT04949113" ;
  schema:name "NADINA"@en ;
  schema:description "Giving the immunotherapy doublet before surgery, instead of nivolumab after, cut the risk of recurrence by about two thirds and let most patients skip further treatment."@en ;
  schema:url <https://onco.cc/trials/nadina/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04949113>, <https://www.nejm.org/doi/full/10.1056/NEJMoa2402604> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2021-07-08" ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/stage-iii-melanoma/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/ctla4/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/ipilimumab/> ;
  onco:institutions <https://onco.cc/institutions/nki/> ;
  onco:terms <https://onco.cc/terms/neoadjuvant-adjuvant/>, <https://onco.cc/terms/efs/>, <https://onco.cc/terms/major-pathological-response/> ;
  onco:people <https://onco.cc/people/georgina-long/>, <https://onco.cc/people/christian-blank/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-nadina-nejm-2024/> .