# OnCo record navigator (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/navigator/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "navigator", "NCT02508532" ;
  schema:name "NAVIGATOR"@en ;
  schema:description "NAVIGATOR showed that avapritinib shrank almost every GIST driven by the PDGFRA D842V mutation, a type that had resisted every earlier drug, and won the drug its approval for that group."@en ;
  schema:url <https://onco.cc/trials/navigator/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02508532> ;
  onco:status "positive" ;
  onco:tag "subtype-trials" ;
  onco:phase "1" ;
  onco:cancers <https://onco.cc/cancers/gist-pdgfra-d842v/>, <https://onco.cc/cancers/gist/>, <https://onco.cc/cancers/sarcoma/> ;
  onco:drugs <https://onco.cc/drugs/avapritinib/> ;
  onco:companies <https://onco.cc/companies/blueprint-medicines/> ;
  onco:people <https://onco.cc/people/michael-heinrich/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-navigator-avapritinib-heinrich-lancet-oncol-2020/> .