# OnCo record nct00317759 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/nct00317759/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "nct00317759", "NCT00317759" ;
  schema:name "Fludarabine before CD8+ antigen-specific T-cell clones in stage IV melanoma (Fred Hutchinson phase 1)"@en ;
  schema:description "A Seattle trial that tested whether giving the chemotherapy drug fludarabine before an infusion of a patient's own melanoma-targeting T cells helped the cells survive. The published report found they lasted about three times longer."@en ;
  schema:url <https://onco.cc/trials/nct00317759/> ;
  schema:dateModified "2026-11-05"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00317759>, <https://doi.org/10.1371/journal.pone.0004749> ;
  onco:status "completed" ;
  onco:phase "1" ;
  schema:startDate "2003-05" ;
  onco:cancers <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/fludarabine/> ;
  onco:institutions <https://onco.cc/institutions/fred-hutch/>, <https://onco.cc/institutions/nci/> ;
  onco:terms <https://onco.cc/terms/endogenous-t-cell-therapy/>, <https://onco.cc/terms/lymphodepletion/> ;
  onco:people <https://onco.cc/people/cassian-yee/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-wallen-fludarabine-ctl-melanoma-plos-one-2009/> .