# OnCo record nct05358249 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/nct05358249/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "nct05358249", "NCT05358249" ;
  schema:name "Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation"@en ;
  schema:alternateName "KontRASt-03"@en ;
  schema:description "A phase 1/2 trial of JDQ443, Trametinib, Ribociclib in non-small-cell lung cancer and small-cell lung cancer, run by Novartis Pharmaceuticals, active and no longer recruiting."@en ;
  schema:url <https://onco.cc/trials/nct05358249/> ;
  schema:dateModified "2026-09-16"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05358249> ;
  onco:status "active" ;
  onco:tag "ctgov-ingest" ;
  onco:phase "1/2" ;
  schema:startDate "2022-10-24" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/sclc/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/kras-g12c-colorectal/>, <https://onco.cc/cancers/kras-g12c-nsclc/> ;
  onco:drugs <https://onco.cc/drugs/jdq443/>, <https://onco.cc/drugs/trametinib/>, <https://onco.cc/drugs/ribociclib/>, <https://onco.cc/drugs/cetuximab/> ;
  onco:companies <https://onco.cc/companies/novartis/> .