# OnCo record nct05548127 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/nct05548127/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "nct05548127", "NCT05548127" ;
  schema:name "TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)"@en ;
  schema:alternateName "TACTIVE-U"@en ;
  schema:description "A phase 1/2 trial of Vepdegestrant and Abemaciclib in advanced solid tumours, run by Pfizer, active and no longer recruiting."@en ;
  schema:url <https://onco.cc/trials/nct05548127/> ;
  schema:dateModified "2026-09-16"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05548127> ;
  onco:status "active" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:phase "1/2" ;
  schema:startDate "2023-02-23" ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/> ;
  onco:technologies <https://onco.cc/technologies/cdk46-inhibitor/>, <https://onco.cc/technologies/endocrine-therapy/>, <https://onco.cc/technologies/protac-degrader/> ;
  onco:drugs <https://onco.cc/drugs/vepdegestrant/>, <https://onco.cc/drugs/abemaciclib/> ;
  onco:companies <https://onco.cc/companies/pfizer/> .