# OnCo record nemtabrutinib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/nemtabrutinib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "nemtabrutinib" ;
  schema:name "Nemtabrutinib"@en ;
  schema:description "Nemtabrutinib is Merck's reversible BTK blocker, active against the C481S escape mutation, being tested against ibrutinib and acalabrutinib in first-line CLL."@en ;
  schema:url <https://onco.cc/drugs/nemtabrutinib/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT06136559> ;
  onco:status "phase-3" ;
  onco:modality "Small-molecule non-covalent BTK inhibitor" ;
  onco:cancers <https://onco.cc/cancers/cll/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/btk/> ;
  onco:companies <https://onco.cc/companies/merck/> ;
  onco:trials <https://onco.cc/trials/bellwave-011/>, <https://onco.cc/trials/nct03162536/>, <https://onco.cc/trials/nct05458297/>, <https://onco.cc/trials/nct04728893/>, <https://onco.cc/trials/nct05947851/>, <https://onco.cc/trials/nct05624554/> .