# OnCo record nf2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/nf2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "nf2" ;
  schema:name "NF2"@en ;
  schema:alternateName "NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor"@en, "Merlin"@en, "merlin"@en, "merlin-1"@en, "NF2" ;
  schema:description "NF2 (Merlin) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Mesothelioma, Renal cell carcinoma, Breast cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/nf2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7773>, <https://www.uniprot.org/uniprotkb/P35240/entry>, <https://www.ncbi.nlm.nih.gov/gene/4771>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000186575> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7773>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000186575>, <https://www.uniprot.org/uniprotkb/P35240/entry>, <https://www.ncbi.nlm.nih.gov/gene/4771> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/mesothelioma/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/thyroid/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/head-and-neck/> ;
  onco:drugs <https://onco.cc/drugs/gsk2256098/> ;
  onco:pathways <https://onco.cc/pathways/hippo-yap/> ;
  onco:trials <https://onco.cc/trials/intuitt-nf2/> .