# OnCo record nife (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/nife/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "nife", "NCT03044587" ;
  schema:name "NIFE (AIO-YMO HEP-0315)"@en ;
  schema:alternateName "NIFE"@en ;
  schema:description "The German NIFE trial gave liposomal irinotecan with fluorouracil as a first treatment for bile duct and gallbladder cancer alongside a standard gemcitabine and cisplatin arm, each judged on its own by the share of patients free of progression at four months. It completed with 93 patients."@en ;
  schema:url <https://onco.cc/trials/nife/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03044587>, <https://doi.org/10.1186/s12885-019-6142-y> ;
  onco:status "completed" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/gallbladder/>, <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/biliary-tract-cancer/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/topoisomerase-inhibitors/> ;
  onco:drugs <https://onco.cc/drugs/liposomal-irinotecan/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/leucovorin/>, <https://onco.cc/drugs/gemcitabine-cisplatin/> .