# OnCo record niraparib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/niraparib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "niraparib" ;
  schema:name "Niraparib"@en ;
  schema:alternateName "Niraparib Tosylate Monohydrate and Abiraterone Acetate"@en, "Akeega"@en, "Zejula" ;
  schema:description "Niraparib is a PARP inhibitor approved as maintenance for ovarian cancer regardless of BRCA status, and in prostate cancer with abiraterone."@en ;
  schema:url <https://onco.cc/drugs/niraparib/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Niraparib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q25326660> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Niraparib>, <https://www.nice.org.uk/guidance/terminated/ta1032> ;
  onco:status "approved" ;
  onco:modality "Small-molecule PARP inhibitor" ;
  onco:approval "US 2017: Recurrent ovarian cancer maintenance", "US 2020: First-line ovarian maintenance" ;
  onco:related <https://onco.cc/biomarkers/brca-germline/>, <https://onco.cc/biomarkers/hrd-positive/> ;
  onco:cancers <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/high-grade-serous-ovarian-cancer/>, <https://onco.cc/cancers/prostate-mcrpc/>, <https://onco.cc/cancers/platinum-sensitive-ovarian-cancer/> ;
  onco:technologies <https://onco.cc/technologies/parp-inhibitor/> ;
  onco:targets <https://onco.cc/targets/parp/> ;
  onco:companies <https://onco.cc/companies/gsk/> ;
  onco:terms <https://onco.cc/terms/prostate-hrr-eligibility/>, <https://onco.cc/terms/prostate-uk-drug-approvals/> ;
  onco:trials <https://onco.cc/trials/nct06915025/>, <https://onco.cc/trials/nct05335993/>, <https://onco.cc/trials/nct04915755/>, <https://onco.cc/trials/nct03431350/>, <https://onco.cc/trials/nct06682780/>, <https://onco.cc/trials/nct04497844/>, <https://onco.cc/trials/nct03602859/>, <https://onco.cc/trials/nct04641247/>, <https://onco.cc/trials/nct06077877/> .